Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524528 | 0.82 | ADRA1A (0.68) | ADRA1ATAAR1AOC3CA12CA1 | |
| SCHEMBL5971447 | 0.82 | APLNR (0.59) | ADRA1ATAAR1APLNRCYP1A2CA12 | |
| SCHEMBL8558574 | 0.78 | CA12 (0.65) | CYP1A2CYP2A6PDE10ACA12CA1 | |
| SCHEMBL23371163 | 0.72 | CYP1A2 (0.56) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL30092293 | 0.72 | CYP1A2 (0.56) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL23980701 | 0.72 | KDM4E (0.49) | PDE10ASLC2A1HTR2A | |
| SCHEMBL6891918 | 0.71 | CYP1A2 (0.71) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL7456084 | 0.71 | CYP1A2 (0.71) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL443528 | 0.71 | CYP2A6 (0.80) | CYP1A2CYP2A6CA12CA1CA2 | |
| SCHEMBL2249185 | 0.71 | CYP1A2 (0.71) | CYP1A2CYP2A6CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222542-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-04 | — | — | WO | disclosed |