Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980757 | 0.90 | TP53 (0.34) | TP53LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL31707542 | 0.90 | TP53 (0.34) | TP53LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL23980854 | 0.81 | LTB4R (0.39) | LTB4RLTB4R2CYP11B1CYP11B2MAPT | |
| SCHEMBL30217500 | 0.77 | LTB4R (0.40) | LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL30275375 | 0.77 | PTGDR2 (0.40) | LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL23980921 | 0.77 | LTB4R (0.40) | LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL23980920 | 0.77 | PTGDR2 (0.40) | LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL23980810 | 0.73 | GLP1R (0.43) | LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL28949266 | 0.70 | ADRA2A (0.52) | LTB4RLTB4R2CYP11B1CYP11B2 | |
| SCHEMBL30217488 | 0.70 | ADRA2A (0.52) | LTB4RLTB4R2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219019-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-11-04 | — | — | WO | disclosed |