Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949266 | 1.00 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CCHRNB4CHRNA3 | |
| SCHEMBL28949267 | 0.87 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CCHRNB4CHRNA3 | |
| SCHEMBL23980920 | 0.86 | PTGDR2 (0.40) | ADRA2AADRA2BADRA2CFFAR1CYP11B1 | |
| SCHEMBL30275375 | 0.86 | PTGDR2 (0.40) | ADRA2AADRA2BADRA2CFFAR1CYP11B1 | |
| SCHEMBL23980921 | 0.83 | LTB4R (0.40) | ADRA2AADRA2BADRA2CFFAR1CYP11B1 | |
| SCHEMBL30217500 | 0.83 | LTB4R (0.40) | ADRA2AADRA2BADRA2CFFAR1CYP11B1 | |
| SCHEMBL29924775 | 0.82 | MAPT (0.44) | ADRA2AADRA2BADRA2CHTR2AHTR2C | |
| SCHEMBL23980935 | 0.81 | CYP11B1 (0.39) | ADRA2AADRA2BADRA2CFFAR1CYP11B1 | |
| SCHEMBL30275367 | 0.81 | CYP11B1 (0.39) | ADRA2AADRA2BADRA2CFFAR1CYP11B1 | |
| SCHEMBL23980854 | 0.80 | LTB4R (0.39) | ADRA2AADRA2BADRA2CCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667250-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-01-31 | — | — | CN | disclosed |