Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LATS1 | O95835 | 5/20 | 0.41 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980746 | 0.85 | POLB (0.47) | ALDH1A1SMN1; SMN2SCN5ASCN3AL3MBTL1 | |
| SCHEMBL23980844 | 0.83 | L3MBTL1 (0.40) | ALDH1A1SMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL23980846 | 0.80 | PRCP (0.40) | LATS1LATS2 | |
| SCHEMBL19924283 | 0.78 | LATS1 (0.43) | LATS1LATS2 | |
| SCHEMBL19924282 | 0.78 | LATS1 (0.43) | LATS1LATS2 | |
| SCHEMBL23980848 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2SCN5ASCN3AL3MBTL1 | |
| SCHEMBL23785461 | 0.70 | TLR8 (0.40) | LATS1LATS2 | |
| SCHEMBL23785495 | 0.70 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2SCN5ASCN3AL3MBTL1 | |
| SCHEMBL28629956 | 0.69 | KMT2A (0.66) | ALDH1A1SMN1; SMN2SCN5ASCN3AL3MBTL1 | |
| SCHEMBL6242176 | 0.69 | KMT2A (0.66) | ALDH1A1SMN1; SMN2SCN5ASCN3AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340141-A1 | TLR8 AGONIST | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340141-A1 | TLR8 AGONIST | TLR8, TLR7, TLR1 | ALDH1A1 3196/4885LATS1 3229/4885LATS2 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.