SCHEMBL23980846

SCHEMBL23980846

CCCCC(C)(CNC(=O)[C@@H]1CCCN1)Nc1nc(Cl)nc2cnccc12

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 3/20 0.40
▸ CCNK O75909 1/20 0.37
▸ CDK12 Q9NYV4 1/20 0.37
▸ LATS1 O95835 14/20 0.37
▸ LATS2 Q9NRM7 8/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23785461 0.90 TLR8 (0.40) PRCPCCNKCDK12LATS1LATS2
SCHEMBL19924282 0.83 LATS1 (0.43) LATS1LATS2
SCHEMBL23980842 0.80 ALDH1A1 (0.44) LATS1LATS2
SCHEMBL23785491 0.79 TLR8 (0.43) PRCP
SCHEMBL23785478 0.74 TLR8 (0.61) —
SCHEMBL23785477 0.74 TLR8 (0.61) —
SCHEMBL23980715 0.74 TLR8 (0.61) —
SCHEMBL23785490 0.72 TLR8 (0.60) —
SCHEMBL23785481 0.72 TLR8 (0.60) —
SCHEMBL19924202 0.70 CYP1A2 (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210340141-A1 TLR8 AGONIST CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2021-11-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210340141-A1 TLR8 AGONIST TLR8, TLR7, TLR1 PRCP 3354/4885CCNK 4849/4885CDK12 4555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback