Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CDA | P32320 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419150 | 1.00 | MAPT (0.60) | MAPTCDALMNATHRBMTOR | |
| SCHEMBL11081361 | 0.81 | ADA (0.57) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11071618 | 0.81 | ADA (0.57) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5508294 | 0.81 | ADA (0.57) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10335631 | 0.81 | ADA (0.57) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2981353 | 0.79 | LMNA (0.56) | MAPTCDALMNATHRBMTOR | |
| SCHEMBL4141706 | 0.79 | LMNA (0.56) | MAPTCDALMNATHRBMTOR | |
| SCHEMBL23982553 | 0.79 | LMNA (0.56) | MAPTCDALMNATHRBMTOR | |
| SCHEMBL20419148 | 0.79 | LMNA (0.56) | MAPTCDALMNATHRBMTOR | |
| SCHEMBL23982252 | 0.79 | MAPT (0.56) | MAPTCDALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338706-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | PER2, CRY1, ADORA2A | MAPT 4035/4885CDA 159/4885LMNA 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.