Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21625725 | 0.99 | DRD2 (0.52) | DRD2DRD4DRD3CHEK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21625720 | 0.99 | DRD2 (0.52) | DRD2DRD4DRD3CHEK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21625715 | 0.98 | DRD2 (0.51) | DRD2DRD4DRD3CHEK1SMN1; SMN2 | |
| SCHEMBL23983071 | 0.91 | NPC1 (0.57) | CHEK1SMN1; SMN2NPC1KMT2AMMP2 | |
| Hydrochloric Acid SCHEMBL21625705 | 0.90 | NPC1 (0.56) | CHEK1SMN1; SMN2NPC1KMT2AMMP2 | |
| SCHEMBL21625737 | 0.85 | SLC2A1 (0.51) | DRD2DRD4DRD3HSD17B1HSD17B2 | |
| Hydrochloric Acid SCHEMBL21625721 | 0.84 | SLC2A1 (0.50) | DRD2DRD4DRD3HSD17B1HSD17B2 | |
| SCHEMBL23983059 | 0.84 | TLR9 (0.49) | DRD2DRD4DRD3HSD17B1HSD17B2 | |
| SCHEMBL23983072 | 0.81 | DRD2 (0.46) | DRD2DRD4DRD3SMN1; SMN2POLB | |
| SCHEMBL21625732 | 0.81 | HSD17B1 (0.53) | CHEK1SMN1; SMN2HSD17B1HSD17B2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340119-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | HEXAPHARMATEC CO., LTD. (KR) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340119-A1 | NOVEL CATECHOL DERIVATIVES OR SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | COMT, TYR, REN | DRD2 158/4885DRD4 179/4885DRD3 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.