SCHEMBL239835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13948475	0.88	TDP1 (0.66)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL3469730	0.88	TDP1 (0.66)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL11392954	0.85	TDP1 (0.50)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL26640463	0.85	TDP1 (0.50)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL9840041	0.83	PKM (0.61)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL1667359	0.83	TDP1 (0.76)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL9439703	0.81	TDP1 (0.67)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL17094937	0.79	TDP1 (0.54)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL7762555	0.78	ALDH1A1 (0.43)	TDP1TSHRALDH1A1TP53MAPT
	SCHEMBL5681759	0.78	IRAK4 (0.40)	TDP1TSHRALDH1A1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.