Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 14/20 | 0.41 |
| ▸ | LPL | P06858 | 13/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25230232 | 0.98 | F11 (0.42) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL18197394 | 0.84 | ROCK1 (0.43) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL1284600 | 0.84 | F11 (0.45) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL26988116 | 0.83 | F11 (0.44) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL29901092 | 0.81 | LIPG (0.44) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL23336941 | 0.81 | LPL (0.44) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL4815568 | 0.81 | LPL (0.44) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL16831631 | 0.81 | LIPG (0.44) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL29418793 | 0.81 | LPL (0.44) | F11LIPGLPLROCK1CA1 | |
| SCHEMBL3226225 | 0.81 | LIPG (0.44) | F11LIPGLPLROCK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219070-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2021-11-04 | — | — | WO | disclosed |