Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.62 |
| ▸ | ESR1 | P03372 | 4/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | YES1 | P07947 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28180041 | 1.00 | ESR2 (0.62) | ESR2ESR1CYP19A1MAOAMAOB | |
| Garbanzol SCHEMBL29370332 | 0.92 | ESR1 (0.73) | ESR2ESR1CYP19A1MAOAMAOB | |
| Garbanzol SCHEMBL9663852 | 0.92 | ESR1 (0.73) | ESR2ESR1CYP19A1MAOAMAOB | |
| Garbanzol SCHEMBL29929200 | 0.92 | ESR1 (0.73) | ESR2ESR1CYP19A1MAOAMAOB | |
| Dihydrobinetin SCHEMBL18177341 | 0.85 | SYNJ2 (0.64) | ESR2ESR1CYP19A1RETKDR | |
| Dihydrorobinetin SCHEMBL30799354 | 0.85 | SYNJ2 (0.64) | ESR2ESR1CYP19A1RETKDR | |
| Dihydrobinetin SCHEMBL432880 | 0.85 | SYNJ2 (0.64) | ESR2ESR1CYP19A1RETKDR | |
| Dihydrorobinetin SCHEMBL432879 | 0.85 | SYNJ2 (0.64) | ESR2ESR1CYP19A1RETKDR | |
| Fustin SCHEMBL13583362 | 0.84 | IDO1 (0.77) | ESR2ESR1CYP19A1IDO1NSD2 | |
| Fustin SCHEMBL13640269 | 0.84 | IDO1 (0.77) | ESR2ESR1CYP19A1IDO1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
| EP-1856085-A1 | FLAVONOID COMPOUNDS AND USES THEREOF | Howard Florey Institute of Experimental Physiology and Medicine (AU) | 2007-11-21 | — | — | EP | claimed |
| WO-2006094357-A1 | FLAVONOID COMPOUNDS AND USES THEREOF | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2006-09-14 | — | — | WO | claimed |
| US-8017649-B2 | Flavonoid compounds and uses thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2011-09-13 | — | — | US | disclosed |
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | ESR2 2310/4885ESR1 2185/4885CYP19A1 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.