SCHEMBL2398482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2399973	1.00	TSHR (0.43)	TSHRALDH1A1CYP2C19CYP1A2MEN1
	SCHEMBL2398897	0.97	TSHR (0.45)	TSHRALDH1A1CYP2C19CYP1A2MEN1
	SCHEMBL3690416	0.88	TSHR (0.43)	TSHRALDH1A1CYP2C19CYP1A2MEN1
	SCHEMBL14262135	0.88	TSHR (0.43)	TSHRALDH1A1CYP2C19CYP1A2MEN1
	Hydrochloric Acid SCHEMBL6032005	0.88	TSHR (0.59)	TSHRALDH1A1CYP2C19CYP1A2LMNA
	Bromide SCHEMBL27973525	0.88	TSHR (0.59)	TSHRALDH1A1CYP2C19CYP1A2CA2
	SCHEMBL2397649	0.88	CYP2C19 (0.40)	TSHRALDH1A1CYP2C19CYP1A2MEN1
	SCHEMBL13293941	0.87	TSHR (0.50)	TSHRALDH1A1CYP2C19CYP1A2MEN1
	SCHEMBL14586416	0.87	ALDH1A1 (0.32)	TSHRALDH1A1CYP2C19CYP1A2KDM1A
	SCHEMBL21015546	0.87	ALDH1A1 (0.32)	TSHRALDH1A1CYP2C19CYP1A2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.