Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988372 | 0.89 | CYP2C9 (0.48) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL23988441 | 0.87 | ATP4A (0.46) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL23988378 | 0.83 | CYP2C9 (0.40) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL23988389 | 0.82 | ATP4A (0.58) | KDM4EALDH1A1MAPTKMT2ACYP2C9 | |
| SCHEMBL23988282 | 0.81 | RUNX1 (0.52) | KDM4EALDH1A1MAPTCYP2C9SLC22A2 | |
| SCHEMBL23988369 | 0.80 | CYP2C9 (0.63) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL23988510 | 0.79 | KMT2A (0.61) | KDM4EALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL13607834 | 0.78 | MAPT (0.63) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL23988437 | 0.76 | NPC1 (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL23988364 | 0.76 | ATP4A (0.46) | KDM4EALDH1A1MAPTKMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202796-A1 | CXCL10 Inhibitors | LAPKO INC, dba AFECTA PHARMACEUTICALS | 2022-06-30 | — | — | US | disclosed |
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202796-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | KDM4E 3648/4885ALDH1A1 3507/4885SMN1; SMN2 3416/4885 |
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | KDM4E 3648/4885ALDH1A1 3507/4885SMN1; SMN2 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.