Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 4/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 4/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 4/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 4/20 | 0.40 |
| ▸ | ATP4A | P20648 | 4/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 4/20 | 0.40 |
| ▸ | ATP4B | P51164 | 4/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 4/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 4/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988364 | 0.93 | ATP4A (0.46) | ALDH1A1HPGDKDM4ELMNAATP1A1 | |
| SCHEMBL23988422 | 0.89 | KMT2A (0.49) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL23988277 | 0.88 | ATP4A (0.49) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL23988441 | 0.84 | ATP4A (0.46) | ALDH1A1HPGDKDM4EHTTLMNA | |
| SCHEMBL23988595 | 0.84 | ATP4A (0.58) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL23988287 | 0.83 | ATP4A (0.48) | ALDH1A1HPGDKDM4ELMNAATP1A1 | |
| SCHEMBL23988464 | 0.80 | ATP4A (0.47) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL23988372 | 0.80 | CYP2C9 (0.48) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL23988352 | 0.79 | KMT2A (0.53) | ALDH1A1HPGDKDM4ENPC1RAB9A | |
| SCHEMBL23988399 | 0.79 | KMT2A (0.44) | ALDH1A1HPGDKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | ALDH1A1 3507/4885HPGD 606/4885KDM4E 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.