Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264096 | 0.86 | JAK1 (0.42) | TSHRL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL12504043 | 0.84 | GAA (0.43) | TSHRHSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL13805669 | 0.82 | L3MBTL1 (0.47) | TSHRL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL19116732 | 0.81 | HTT (0.45) | GAAL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL18534152 | 0.81 | LMNA (0.53) | TSHRHSD17B10GAAL3MBTL1LMNA | |
| SCHEMBL24211171 | 0.81 | L3MBTL1 (0.42) | TSHRGAAL3MBTL1LMNAHTT | |
| SCHEMBL2749841 | 0.79 | L3MBTL1 (0.38) | TSHRHSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL18869380 | 0.79 | L3MBTL1 (0.41) | TSHRHSD17B10HPGDGAAL3MBTL1 | |
| SCHEMBL15447742 | 0.79 | ALDH1A1 (0.43) | TSHRHPGDGAAL3MBTL1LMNA | |
| SCHEMBL18563593 | 0.79 | HPGD (0.43) | TSHRHSD17B10HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904348-A1 | AMINOPYRIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2021-11-03 | — | — | EP | disclosed |