Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | WDR5 | P61964 | 3/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348110 | 0.90 | WDR5 (0.58) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL5348112 | 0.90 | WDR5 (0.58) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL23988442 | 0.90 | WDR5 (0.58) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL21945694 | 0.88 | SARM1 (0.61) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL6440042 | 0.88 | SARM1 (0.61) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL23988439 | 0.88 | SARM1 (0.61) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL29323850 | 0.87 | SARM1 (0.53) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL8119116 | 0.86 | KMT2A (0.45) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL6877030 | 0.86 | SARM1 (0.52) | KMT2AWDR5SARM1NPC1RAB9A | |
| SCHEMBL929030 | 0.86 | KMT2A (0.43) | KMT2AWDR5SARM1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | KMT2A 3380/4885WDR5 3395/4885SARM1 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.