SCHEMBL23988555

SCHEMBL23988555

CN1c2ccccc2C2(c3ccccc31)c1ccccc1[Si](C)(C)c1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.37
LMNA P02545 6/20 0.37
HTT P42858 5/20 0.37
KDM4E B2RXH2 5/20 0.37
HCRTR1 O43613 1/20 0.37
MAOA P21397 1/20 0.35
AKR1B1 P15121 1/20 0.33
RAD52 P43351 1/20 0.33
MEN1 O00255 7/20 0.33
KMT2A Q03164 7/20 0.33
ALDH1A1 P00352 5/20 0.33
TSHR P16473 3/20 0.33
THRB P10828 2/20 0.33
RECQL P46063 2/20 0.33
GAA P10253 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TTR P02766 1/20 0.32
CES1 P23141 1/20 0.32
CASP1 P29466 2/20 0.32
MAPK1 P28482 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21008784 0.82 MAPT (0.35) MAPTLMNAHTTKDM4EHCRTR1
SCHEMBL21008868 0.81 CNR1 (0.31)
SCHEMBL11990876 0.80 MAPT (0.41) MAPTLMNAHTTKDM4EHCRTR1
SCHEMBL11990871 0.78 MAPT (0.42) MAPTLMNAKDM4EMEN1KMT2A
SCHEMBL10128247 0.78 MAOA (0.44) MAPTLMNAHTTKDM4EMAOA
SCHEMBL23056710 0.76 HTT (0.49) MAPTLMNAHTTKDM4EHCRTR1
SCHEMBL19754284 0.74 CES1 (0.48) MAPTLMNAHTTKDM4EHCRTR1
SCHEMBL23638904 0.73 GAA (0.41) MAPTLMNAHTTKDM4EHCRTR1
SCHEMBL24044001 0.73 LMNA (0.40) MAPTLMNAKDM4EAKR1B1MEN1
SCHEMBL20202031 0.73 MAPT (0.39) MAPTLMNAHTTKDM4EHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210363416-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT AND SYNTHESIZING METHOD THEREOF WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-11-25 US disclosed
US-11177442-B1 Thermally activated delayed fluorescence material and organic light emitting diode display device WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-11-16 US disclosed
US-20210336150-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DIODE DISPLAY DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11177442-B1 Thermally activated delayed fluorescence material and organic light emitting diode display device CCND1, CCND2, TRPA1 MAPT 580/4885LMNA 2286/4885HTT 4675/4885
US-20210336150-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DIODE DISPLAY DEVICE CCND1, CCND2, TRPA1 MAPT 580/4885LMNA 2286/4885HTT 4675/4885
US-20210363416-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT AND SYNTHESIZING METHOD THEREOF HSF1, TBCA, CPSF7 MAPT 2066/4885LMNA 2168/4885HTT 2573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.