Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 7/20 | 0.39 |
| ▸ | ATP4B | P51164 | 7/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 6/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 6/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 6/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 6/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 6/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 6/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 6/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 6/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | RUNX1 | Q01196 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988588 | 0.92 | NPC1 (0.46) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988445 | 0.92 | ATP4A (0.47) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988411 | 0.89 | KMT2A (0.47) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988399 | 0.89 | KMT2A (0.44) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL24571950 | 0.84 | KMT2A (0.41) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988489 | 0.84 | RUNX1 (0.51) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988401 | 0.84 | CYP3A4 (0.45) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988402 | 0.83 | NPC1 (0.46) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988413 | 0.81 | ATP4A (0.43) | KMT2AMEN1HTTATP4AATP4B | |
| SCHEMBL23988398 | 0.81 | ATP4A (0.54) | KMT2AMEN1HTTATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | AFECTA PHARMACEUTICALS, INC. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338650-A1 | CXCL10 Inhibitors | CXCL10, CCL5, CCL11 | KMT2A 3380/4885MEN1 3946/4885HTT 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.