SCHEMBL2398866

SCHEMBL2398866

CC(=O)Cc1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
GFER P55789 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.44
CA2 P00918 1/20 0.41
MAOA P21397 2/20 0.41
FDPS P14324 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
CNR2 P34972 1/20 0.41
EPHX2 P34913 1/20 0.40
DHFR P00374 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL11195976 0.96 POLB (0.48) POLBCYP3A4TSHRTDP1GFER
SCHEMBL8403545 0.87 POLB (0.61) POLBTSHRALDH1A1CA2LMNA
SCHEMBL4617406 0.84 ALDH1A1 (0.60) ALDH1A1LOXL2CYP1A2NPC1MAPT
SCHEMBL20157279 0.82 CES2 (0.43) CYP3A4TSHRTDP1GFERALDH1A1
SCHEMBL27499987 0.82 TAAR1 (0.52) POLBTSHRTDP1ALDH1A1LOXL2
SCHEMBL11079658 0.81 KDM4E (0.52) POLBLOXL2CA2SMN1; SMN2
SCHEMBL5272776 0.80 GFER (0.50) CYP3A4TSHRTDP1GFERALDH1A1
SCHEMBL10775630 0.80 POLB (0.55) POLBTDP1ALDH1A1CA2
SCHEMBL27727263 0.80 ALDH1A1 (0.50) CYP3A4TSHRTDP1GFERALDH1A1
SCHEMBL8269170 0.78 ALDH1A1 (0.44) ALDH1A1LMNANPC1RAB9ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751904-A Preparation method of bio-based epoxy resin/carbon fiber composite material 中南民族大学 2025-04-04 CN claimed
CN-119751906-A Bio-based hyperbranched epoxy resin/bisphenol A epoxy resin composite resin containing imide structure 中南民族大学 2025-04-04 CN claimed
CN-119285900-A High-performance degradable imide skeleton hyperbranched epoxy resin-carbon fiber composite material and preparation method thereof 中南民族大学 2025-01-10 CN claimed
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN claimed
CN-115703892-B High-performance degradable epoxy resin-carbon fiber composite material and preparation method thereof 中南民族大学 2024-06-11 CN claimed
CN-117327244-A Self-sensitization type radiochromic polyurethane elastomer and preparation method thereof 四川大学 2024-01-02 CN claimed
CN-115703892-A High-performance degradable epoxy resin-carbon fiber composite material and preparation method thereof 中南民族大学 2023-02-17 CN claimed
CN-111647137-B Bio-based degradable hyperbranched epoxy resin and preparation method thereof 武汉工程大学 2022-05-17 CN claimed
CN-111647137-A Bio-based degradable hyperbranched epoxy resin and preparation method thereof 武汉工程大学 2020-09-11 CN claimed
CN-108609610-B Method for preparing high-strength carbon nanotube film by using mercaptan-olefin click reaction 中南民族大学 2020-01-24 CN claimed
CN-120040677-A Recoverable high-performance bionic supermolecular elastomer and preparation method thereof 中南民族大学 2025-05-27 CN disclosed
CN-119751906-A Bio-based hyperbranched epoxy resin/bisphenol A epoxy resin composite resin containing imide structure 中南民族大学 2025-04-04 CN disclosed
CN-119751904-A Preparation method of bio-based epoxy resin/carbon fiber composite material 中南民族大学 2025-04-04 CN disclosed
US-12264169-B2 Heteroaryl inhibitors of PDE4 Tetra Discovery Partners (US) 2025-04-01 US disclosed
WO-2025054339-A1 TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT ARCUS BIOSCIENCES, INC. (US) 2025-03-13 WO disclosed
EP-0236624-B1 SUBSTITUTED PHENYL ETHANOL AMINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1993-08-11 EP disclosed
US-5153210-A Hypoglycemic agent, animal growth regulator; veterinary medicine BEECHAM GROUP P.L.C. (GB) 1992-10-06 US disclosed
US-4933336-A Thiadiazinone, oxadiazinone and triazinone derivatives, and their use for treating acute or chronic heart disease LABORATOIRES SOBIO S.A. (FR) 1990-06-12 US disclosed
EP-0303418-A2 Substituted indolones, useful in the treatment of heart or asthmatic diseases SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) 1989-02-15 EP disclosed
EP-0236624-A2 Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1987-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12264169-B2 Heteroaryl inhibitors of PDE4 PDE4A, PDE4B, PDE4C POLB 2686/4885CYP3A4 248/4885TSHR 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.