Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 11/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009679 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNAPTBP1 | |
| SCHEMBL7965189 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAPTBP1DRD3GNAI3 | |
| SCHEMBL8140198 | 0.77 | DRD3 (0.44) | DRD3DRD2DRD4 | |
| SCHEMBL23507377 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAPTBP1DRD3 | |
| SCHEMBL30859666 | 0.76 | HPGD (0.45) | ALDH1A1 | |
| SCHEMBL15508594 | 0.74 | DRD3 (0.44) | DRD3DRD2DRD4 | |
| SCHEMBL24438350 | 0.72 | DRD3 (0.46) | DRD3DRD2DRD4 | |
| SCHEMBL13597080 | 0.71 | GNAI3 (0.53) | GNAI3GNAO1GNAI1 | |
| SCHEMBL3374356 | 0.71 | DRD3 (0.44) | DRD3DRD2DRD4 | |
| SCHEMBL26617906 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNAPTBP1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222875-A1 | METHODS OF USING ALK2 INHIBITORS | KEROS THERAPEUTICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |