Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140198 | 0.90 | DRD3 (0.44) | DRD3DRD2DRD4 | |
| SCHEMBL7970805 | 0.82 | ACKR3 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL23988770 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNAPTBP1DRD3GNAI3 | |
| SCHEMBL13772826 | 0.76 | GNAI3 (0.40) | ALDH1A1LMNAPTBP1KMT2AGNAI3 | |
| SCHEMBL3376484 | 0.73 | ADH1C (0.43) | KMT2ADRD3DRD2DRD4 | |
| SCHEMBL10416391 | 0.73 | ADH1C (0.43) | KMT2ADRD3DRD2DRD4 | |
| SCHEMBL13616203 | 0.72 | KMT2A (0.40) | ALDH1A1KMT2A | |
| SCHEMBL3431068 | 0.72 | KMT2A (0.40) | ALDH1A1KMT2A | |
| SCHEMBL3068209 | 0.72 | L3MBTL3 (0.56) | ALDH1A1KMT2A | |
| SCHEMBL30859666 | 0.72 | HPGD (0.45) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268381-B1 | Taxane derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-1044971-A1 | TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-10-18 | — | — | EP | disclosed |