Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2398896

C=CC(=O)OC(O)CC[N+](C)(C)C.[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 3/20 0.33
CHRM3 known ✓ P20309 3/20 0.33
CHRM2 known ✓ P08172 2/20 0.32
ACHE known ✓ P22303 1/20 0.32
TSHR P16473 7/20 0.36
CHRM5 P08912 3/20 0.33
MAPT P10636 3/20 0.33
BLM P54132 2/20 0.33
CHRM4 P08173 2/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
ALDH1A1 P00352 4/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
HPGD P15428 1/20 0.32
GALR3 O60755 1/20 0.32
LMNA P02545 2/20 0.31
APEX1 P27695 1/20 0.31
ADRA2A P08913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6559959 0.98 TSHR (0.37) TSHRCHRM5CHRM1CHRM3MAPT
Hydrochloric Acid SCHEMBL2365721 0.86 TSHR (0.34) TSHRCHRM1CHRM3CHRM2SMN1; SMN2
SCHEMBL6557499 0.84 TSHR (0.35) TSHRCHRM1CHRM3CHRM2SMN1; SMN2
Hydrochloric Acid SCHEMBL9682165 0.81 MAPT (0.32) CHRM5CHRM1CHRM3MAPTBLM
SCHEMBL26503 0.77 TSHR (0.44) TSHRCHRM1CHRM3SMN1; SMN2ALDH1A1
SCHEMBL11233280 0.77 TSHR (0.41) TSHRMAPTSMN1; SMN2ALDH1A1TP53
Hydrochloric Acid SCHEMBL7049934 0.76 MEN1 (0.40) TSHRCHRM5CHRM1CHRM3MAPT
SCHEMBL27143080 0.76 TSHR (0.42) TSHRCHRM1CHRM3SMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL2031939 0.75 CHRM1 (0.37) TSHRCHRM5CHRM1CHRM3MAPT
SCHEMBL2119381 0.75 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220332660-A1 Stable Aqueous Compositions of Fertilizer and Agriculturally Active Compound BASF SE (DE) 2022-10-20 US disclosed
US-20220287301-A1 POLYMERS FOR SPRAY DRIFT CONTROL OF PESTICIDE SPRAY BASF SE (DE) 2022-09-15 US disclosed
EP-4038038-A1 STABLE AQUEOUS COMPOSITIONS OF FERTILIZER AND AGRICULTURALLY ACTIVE COMPOUND BASF SE (DE) 2022-08-10 EP disclosed
EP-4025053-A1 POLYMERS FOR SPRAY DRIFT CONTROL OF PESTICIDE SPRAY BASF SE (DE) 2022-07-13 EP disclosed
WO-2021063885-A1 STABLE AQUEOUS COMPOSITIONS OF FERTILIZER AND AGRICULTURALLY ACTIVE COMPOUND BASF SE (DE) 2021-04-08 WO disclosed
US-20110230619-A1 Nitrogen-Containing Organosilicon Graft Copolymers EVONIK GOLDSCHMIDT GMBH (DE) 2011-09-22 US disclosed
US-7678308-B2 Molded woody article and process for producing molded woody article TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) 2010-03-16 US disclosed
EP-1731279-B1 MOLDED WOODY ARTICLE AND PROCESS FOR PRODUCING MOLDED WOODY ARTICLE TOYOTA BOSHOKU KABUSHIKI KAISY (JP) 2009-09-02 EP disclosed
US-20070197736-A1 Molded Woody Article And Process For Producing Molded Woody Article NOF CORPORATION (JP) 2007-08-23 US disclosed
EP-1731279-A1 MOLDED WOODY ARTICLE AND PROCESS FOR PRODUCING MOLDED WOODY ARTICLE Toyota Boshoku Kabushiki Kaisya (JP) 2006-12-13 EP disclosed
WO-2002015854-A1 USE OF HYDROPHILIC GRAFT COPOLYMERS WITH N-VINYLAMINE AND/OR OPEN-CHAINED N-VINYLAMIDE UNITS IN COSMETIC FORMULATIONS BASF AKTIENGESELLSCHAFT (DE) 2002-02-28 WO disclosed
WO-2002011686-A2 HAIR STYLING COMPOSITION UNILEVER PLC (GB) 2002-02-14 WO disclosed
EP-1161459-A1 INTERPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2001-12-12 EP disclosed
EP-1154751-A1 FORMULATIONS OF HAIR COSMETICS BASF AKTIENGESELLSCHAFT (DE) 2001-11-21 EP disclosed
EP-1136070-A1 Soft capsules comprising polymerisates of vinylesters and polyethers, use and preparation thereof BASF AKTIENGESELLSCHAFT (DE) 2001-09-26 EP disclosed
WO-2001013884-A2 COSMETIC AND/OR PHARMACEUTICAL PREPARATIONS WITH POLYMERS CONTAINING POLYSILOXANES AND THE USES THEREOF BASF AKTIENGESELLSCHAFT (DE) 2001-03-01 WO disclosed
WO-2000049998-A1 FORMULATIONS OF HAIR COSMETICS BASF AKTIENGESELLSCHAFT (DE) 2000-08-31 WO disclosed
WO-2000047631-A1 INTERPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2000-08-17 WO disclosed
EP-0998254-A2 USE OF POLYMERS CONTAINING POLYSILOXANE FOR COSMETIC FORMULATIONS BASF AKTIENGESELLSCHAFT (DE) 2000-05-10 EP disclosed
WO-1999004750-A2 USE OF POLYMERS CONTAINING POLYSILOXANE FOR COSMETIC FORMULATIONS BASF AKTIENGESELLSCHAFT (DE) 1999-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220287301-A1 POLYMERS FOR SPRAY DRIFT CONTROL OF PESTICIDE SPRAY DDT, PARG, PLD2 CHRM1 1457/4885CHRM3 607/4885CHRM2 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.