Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ENO1 | P06733 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700706 | 0.69 | — | — | |
| SCHEMBL25244935 | 0.67 | TSHR (0.50) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL8031151 | 0.67 | TSHR (0.50) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL50366 | 0.66 | MEN1 (0.58) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL30520176 | 0.65 | MEN1 (0.50) | MEN1LMNAHPGDTSHRBLM | |
| Fosfonet SCHEMBL15612 | 0.64 | — | — | |
| SCHEMBL5000897 | 0.63 | MEN1 (0.48) | MEN1LMNAHPGDTSHRBLM | |
| Fosfonet SCHEMBL9162319 | 0.62 | — | — | |
| Fosfonet SCHEMBL4607410 | 0.62 | MEN1 (0.93) | MEN1LMNAHPGDTSHRBLM | |
| Fosfonet SCHEMBL2801407 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372601-B2 | Compositions and methods for the synthesis of APPA-containing peptides | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (US) | 2013-02-12 | — | — | US | disclosed |
| US-20110217734-A1 | COMPOSITIONS AND METHODS FOR THE SYNTHESIS OF APPA-CONTAINING PEPTIDES | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN | 2011-09-08 | — | — | US | disclosed |