Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 2/20 | 0.43 |
| ▸ | NT5E | P21589 | 6/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992563 | 0.92 | ADORA3 (0.41) | HINT1NT5EADORA2AADORA2BADORA3 | |
| SCHEMBL26223203 | 0.84 | ADORA3 (0.40) | HINT1NT5EADORA2AADORA2BADORA3 | |
| SCHEMBL19187157 | 0.83 | ST6GAL1 (0.36) | — | |
| SCHEMBL23992572 | 0.82 | HINT1 (0.42) | HINT1NT5EHSP90B1ADORA2AADORA2B | |
| SCHEMBL23992624 | 0.79 | HINT1 (0.45) | HINT1NT5EHSP90B1ADORA2AADORA2B | |
| SCHEMBL19187636 | 0.79 | ADORA3 (0.32) | HINT1NT5EADORA2AADORA2BADORA3 | |
| SCHEMBL21116657 | 0.79 | BCHE (0.47) | ADORA2BADORA3 | |
| SCHEMBL20059195 | 0.78 | CYP3A4 (0.40) | NT5E | |
| SCHEMBL23992609 | 0.78 | ADORA3 (0.41) | HINT1NT5EADORA2AADORA2BADORA3 | |
| SCHEMBL19187113 | 0.77 | ADORA3 (0.31) | HINT1ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216722-A1 | STEREOSELECTIVE PROCESS OF MANUFACTURE OF PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2021-10-28 | — | — | WO | disclosed |