Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 11/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19187694 | 0.90 | ST6GAL1 (0.35) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL20845803 | 0.88 | ST6GAL1 (0.34) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL20058651 | 0.88 | ST6GAL1 (0.36) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL20058982 | 0.88 | ST6GAL1 (0.36) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL20059195 | 0.85 | CYP3A4 (0.40) | ST6GAL1 | |
| SCHEMBL19187061 | 0.83 | L3MBTL1 (0.35) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL23992605 | 0.83 | HINT1 (0.43) | — | |
| SCHEMBL21116319 | 0.82 | LMNA (0.35) | ST6GAL1LMNATHRBMTORMDM2 | |
| SCHEMBL20059130 | 0.82 | — | — | |
| SCHEMBL22110529 | 0.82 | ST6GAL1 (0.31) | ST6GAL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2696679-B1 | 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2017-08-02 | — | — | EP | disclosed |