Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25006008 | 0.82 | TRPV4 (0.46) | SLC6A4ARCYP11B2CYP11B1 | |
| SCHEMBL23993559 | 0.81 | SLC6A4 (0.38) | SLC6A4HTR2AARMAOAMAOB | |
| SCHEMBL2474594 | 0.80 | FFAR1 (0.52) | ARUSP30S1PR1S1PR5S1PR3 | |
| SCHEMBL4509439 | 0.80 | FFAR1 (0.52) | ARUSP30S1PR1S1PR5S1PR3 | |
| SCHEMBL23995539 | 0.80 | AR (0.48) | AR | |
| SCHEMBL23993565 | 0.80 | SLC6A4 (0.49) | TSHRSLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL25004524 | 0.79 | SLC6A4 (0.38) | SLC6A4HTR2AHTR2CHTR2BAR | |
| SCHEMBL13326647 | 0.77 | S1PR1 (0.41) | ARUSP30S1PR1S1PR5S1PR3 | |
| SCHEMBL15112858 | 0.77 | USP30 (0.47) | TSHRHTR2CARUSP30CYP11B2 | |
| SCHEMBL31335 | 0.75 | USP30 (0.46) | TSHRARUSP30CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | TSHR 2272/4885SLC6A4 1120/4885HTR2A 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.