Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25005549 | 0.79 | GRIA4 (0.46) | KDM1AMAOAMAOBHRH3 | |
| SCHEMBL22210214 | 0.79 | DRD3 (0.55) | DRD3DRD2KDM1AMAOAMAOB | |
| SCHEMBL27048506 | 0.76 | HTR2A (0.50) | HTR2CHTR2BALOX5 | |
| SCHEMBL23993595 | 0.76 | HTR2A (0.50) | KDM1AMAOAMAOBHRH3HTR2C | |
| SCHEMBL13251359 | 0.76 | HTR2A (0.50) | KDM1AMAOAMAOBHRH3HTR2C | |
| SCHEMBL23993596 | 0.76 | HTR2A (0.51) | KDM1AHTR2CHTR2B | |
| SCHEMBL23995533 | 0.75 | HTR2C (0.50) | DRD3DRD2KDM1AMAOAMAOB | |
| SCHEMBL23992996 | 0.74 | CYP11B2 (0.44) | KDM1A | |
| SCHEMBL25005228 | 0.73 | HTR2C (0.56) | KDM1AMAOAMAOBHTR2CHTR2B | |
| SCHEMBL23995526 | 0.72 | HTR2C (0.54) | DRD3DRD2KDM1AHRH3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222522-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |