Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019855 | 0.87 | HTR2C (0.57) | HTR2CHTR2AHTR2BALOX5SLC9A1 | |
| SCHEMBL9019856 | 0.87 | HTR2C (0.57) | HTR2CHTR2AHTR2BALOX5SLC9A1 | |
| SCHEMBL8098456 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BALOX5SLC9A1 | |
| SCHEMBL8098198 | 0.87 | HTR2C (0.54) | HTR2CHTR2AHTR2BALOX5SLC9A1 | |
| SCHEMBL25004988 | 0.81 | ALOX5 (0.45) | HTR2CHTR2AHTR2BALOX5KDM1A | |
| SCHEMBL8332790 | 0.81 | SLC9A1 (0.56) | HTR2CHTR2AHTR2BALOX5SLC9A1 | |
| SCHEMBL8330687 | 0.79 | SLC9A1 (0.54) | HTR2CHTR2AHTR2BALOX5SLC9A1 | |
| SCHEMBL8332241 | 0.79 | ALOX5 (0.55) | HTR2CHTR2AHTR2BALOX5SLC9A1 | |
| SCHEMBL25005229 | 0.79 | KDM1A (0.58) | HTR2CKDM1AMAOAMAOB | |
| SCHEMBL8333649 | 0.79 | HTR2C (0.63) | HTR2CHTR2AHTR2BSLC9A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | HTR2C 1699/4885HTR2A 1593/4885HTR2B 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.