Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399530 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAGAAHPGDSMN1; SMN2 | |
| SCHEMBL14354774 | 0.96 | ALDH1A1 (0.42) | ALDH1A1LMNAGAAHPGDSMN1; SMN2 | |
| SCHEMBL12758256 | 0.94 | TDP1 (0.36) | ALDH1A1LMNAGAAHPGDNPC1 | |
| SCHEMBL12268341 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12758222 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9889301 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9889202 | 0.90 | TSHR (0.40) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL13556968 | 0.88 | TDP1 (0.35) | ALDH1A1LMNAGAAHPGDSMN1; SMN2 | |
| SCHEMBL9889185 | 0.88 | KDM4E (0.40) | ALDH1A1LMNAGAAHPGDSMN1; SMN2 | |
| SCHEMBL4547548 | 0.86 | ALDH1A1 (0.45) | ALDH1A1LMNAGAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120269749-A1 | COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT | L'OREAL (FR) | 2012-10-25 | — | — | US | claimed |
| US-8025867-B2 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2011-09-27 | — | — | US | claimed |
| US-20080305058-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2008-12-11 | — | — | US | claimed |
| EP-1888009-A1 | METHOD FOR PHOTOSTABILIZING A DIBENZOYLMETHANE DERIVATIVE USING A MEROCYANINE SULPHONE DERIVATIVE; PHOTOPROTECTIVE COSMETIC COMPOSITIONS CONTAINING SAID COMBINATION | L'Oréal (FR) | 2008-02-20 | — | — | EP | claimed |
| WO-2006125676-A1 | METHOD FOR PHOTOSTABILIZING A DIBENZOYLMETHANE DERIVATIVE USING A MEROCYANINE SULPHONE DERIVATIVE; PHOTOPROTECTIVE COSMETIC COMPOSITIONS CONTAINING SAID COMBINATION | L'OREAL (FR) | 2006-11-30 | — | — | WO | claimed |
| US-20120269749-A1 | COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT | L'OREAL (FR) | 2012-10-25 | — | — | US | disclosed |
| US-20120269749-A1 | COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT | L'OREAL (FR) | 2012-10-25 | — | — | US | disclosed |
| US-8025867-B2 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2011-09-27 | — | — | US | disclosed |
| US-8025867-B2 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2011-09-27 | — | — | US | disclosed |
| US-8025867-B2 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2011-09-27 | — | — | US | disclosed |
| WO-2011054387-A1 | COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT | L'OREAL (FR) | 2011-05-12 | — | — | WO | disclosed |
| US-20080305058-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2008-12-11 | — | — | US | disclosed |
| US-20080305058-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2008-12-11 | — | — | US | disclosed |
| US-20080305058-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | L'OREAL (FR) | 2008-12-11 | — | — | US | disclosed |
| EP-1888009-A1 | METHOD FOR PHOTOSTABILIZING A DIBENZOYLMETHANE DERIVATIVE USING A MEROCYANINE SULPHONE DERIVATIVE; PHOTOPROTECTIVE COSMETIC COMPOSITIONS CONTAINING SAID COMBINATION | L'Oréal (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125676-A1 | METHOD FOR PHOTOSTABILIZING A DIBENZOYLMETHANE DERIVATIVE USING A MEROCYANINE SULPHONE DERIVATIVE; PHOTOPROTECTIVE COSMETIC COMPOSITIONS CONTAINING SAID COMBINATION | L'OREAL (FR) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269749-A1 | COSMETIC COMPOSITIONS COMPRISING AN ESTER DERIVED FROM 4-CARBOXY-2-PYRROLIDINONE AND A MEROCYANIN SCREENING AGENT; USE OF SAID DERIVATIVE AS A SOLVENT FOR A MEROCYANIN SCREENING AGENT | PYCR1, TYR, PAH | ALDH1A1 661/4885LMNA 1104/4885GAA 2338/4885 |
| US-20080305058-A1 | Photoprotective cosmetic compositions comprising photostabilized dibenzoylmethane compounds and merocyanine sulfone compounds | DDT, DSG1, DSC1 | ALDH1A1 809/4885LMNA 1501/4885GAA 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.