Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | SDCBP | O00560 | 1/20 | 0.37 |
| ▸ | SDC2 | P34741 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796279 | 0.74 | L3MBTL1 (0.56) | HDAC1L3MBTL1NAMPTGAACA1 | |
| SCHEMBL23997378 | 0.73 | LMNA (0.38) | HDAC1LMNA | |
| SCHEMBL17040910 | 0.73 | L3MBTL1 (0.44) | HDAC1L3MBTL1NAMPTGAACA1 | |
| SCHEMBL3180689 | 0.71 | L3MBTL1 (0.61) | HDAC1L3MBTL1NAMPTSDCBPSDC2 | |
| SCHEMBL23775214 | 0.71 | LSS (0.52) | HDAC1L3MBTL1NAMPTSDCBPSDC2 | |
| Acetic Acid SCHEMBL8138998 | 0.71 | SMN1; SMN2 (0.53) | HDAC1L3MBTL1NAMPTGAACA1 | |
| SCHEMBL23997165 | 0.70 | KMT2A (0.41) | HDAC1 | |
| SCHEMBL23885017 | 0.70 | L3MBTL1 (0.51) | HDAC1L3MBTL1NAMPTSDCBPSDC2 | |
| SCHEMBL28177091 | 0.69 | L3MBTL1 (0.46) | HDAC1L3MBTL1NAMPTSDCBPSDC2 | |
| SCHEMBL732456 | 0.69 | NAMPT (0.57) | HDAC1L3MBTL1NAMPTSDCBPSDC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |