Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997631 | 0.86 | SAE1 (0.46) | DPP4DPP7GAAHTTLDHA | |
| SCHEMBL24106651 | 0.85 | DPP4 (0.47) | DPP4DPP7GAAHTTLDHA | |
| SCHEMBL12891269 | 0.79 | LDHA (0.51) | DPP4DPP7GAALDHAALDH1A1 | |
| SCHEMBL23997549 | 0.78 | DPP4 (0.53) | DPP4DPP7LDHAKIF11IDO1 | |
| SCHEMBL6430514 | 0.78 | DPP4 (0.53) | DPP4DPP7LDHAKIF11IDO1 | |
| SCHEMBL12891267 | 0.78 | EPHX1 (0.51) | DPP4DPP7GAAHTTLDHA | |
| SCHEMBL2036339 | 0.78 | DPP4 (0.53) | DPP4DPP7LDHAKIF11IDO1 | |
| SCHEMBL5018923 | 0.78 | IDO1 (0.46) | DPP4DPP7GAAALDH1A1IDO1 | |
| SCHEMBL24106695 | 0.77 | IDO1 (0.46) | DPP4DPP7GAALDHAALDH1A1 | |
| SCHEMBL27360388 | 0.77 | HTT (0.47) | GAAHTTLDHAALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. | 2023-06-08 | — | — | US | disclosed |
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. | 2023-06-08 | — | — | US | disclosed |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | Tonix Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | Tonix Pharmaceuticals, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-11566032-B2 | Radio-protective and chemo-protective substituted thiols | Tonix Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20210388011-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | TONIX PHARMACEUTICALS HOLDING CORP. | 2021-12-16 | — | — | US | disclosed |
| WO-2021226559-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | Tonix Pharmaceuticals, Inc. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174562-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | MGMT, RCOR3, TSPO | DPP4 2414/4885DPP7 2596/4885GAA 4313/4885 |
| US-20210388011-A1 | RADIO-AND CHEMO-PROTECTIVE COMPOUNDS | MGMT, GSTP1, GSTA1 | DPP4 894/4885DPP7 1008/4885GAA 4517/4885 |
| US-11566032-B2 | Radio-protective and chemo-protective substituted thiols | MGMT, GSTP1, GSTA1 | DPP4 757/4885DPP7 853/4885GAA 4449/4885 |
| US-20230138150-A1 | RADIO-PROTECTIVE AND CHEMO-PROTECTIVE SUBSTITUTED THIOLS | MGMT, GSTA1, GSTP1 | DPP4 1408/4885DPP7 1460/4885GAA 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.