Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24013194 | 0.79 | HSD17B10 (0.48) | ACHEPTGS2MAPTALDH1A1HSD17B10 | |
| SCHEMBL1847209 | 0.79 | LOXL2 (0.42) | ACHEMAPTALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL24013189 | 0.77 | MAPT (0.40) | ACHECA1CA2BCHEPTGS2 | |
| SCHEMBL12354045 | 0.76 | HSPB1 (0.44) | ACHECA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL23998042 | 0.75 | HSD17B10 (0.44) | ACHEMAPTALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL25150205 | 0.75 | RECQL (0.53) | ACHEMAPTALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL6747520 | 0.75 | RECQL (0.53) | ACHEMAPTALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL25149380 | 0.73 | MAPT (0.37) | MAPTALDH1A1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL25150270 | 0.73 | RECQL (0.37) | CYP3A4IDO1RECQL | |
| SCHEMBL25150338 | 0.73 | ALDH1A1 (0.43) | MAPTALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021225823-A1 | SYNTHESIS OF VINYLIC PROTECTED ALCOHOL INTERMEDIATES | AMGEN INC. (US) | 2021-11-11 | — | — | WO | disclosed |