Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 5/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | ARAF | P10398 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999630 | 0.94 | LMNA (0.55) | RAB9ANPC1SMN1; SMN2LMNAPGR | |
| SCHEMBL23999626 | 0.94 | LMNA (0.55) | RAB9ANPC1SMN1; SMN2LMNAMAPK13 | |
| SCHEMBL23999635 | 0.89 | POLB (0.56) | RAB9ANPC1SMN1; SMN2LMNAHDAC1 | |
| SCHEMBL23999770 | 0.88 | HDAC3 (0.46) | RAB9ANPC1SMN1; SMN2LMNATDP1 | |
| SCHEMBL23999771 | 0.88 | MEN1 (0.45) | RAB9ANPC1SMN1; SMN2LMNAHDAC1 | |
| SCHEMBL24003736 | 0.87 | RAF1 (0.51) | RAB9ANPC1SMN1; SMN2LMNATDP1 | |
| SCHEMBL30232529 | 0.87 | RAF1 (0.51) | RAB9ANPC1SMN1; SMN2LMNATDP1 | |
| SCHEMBL19888734 | 0.86 | PGR (0.65) | RAB9ANPC1SMN1; SMN2LMNABRAF | |
| SCHEMBL23999769 | 0.86 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2TDP1HDAC1 | |
| SCHEMBL23999774 | 0.86 | GRM4 (0.44) | RAB9ANPC1SMN1; SMN2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | RAB9A 1375/4885NPC1 1175/4885SMN1; SMN2 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.