Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915942 | 1.00 | KDM5A (0.46) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL2397444 | 1.00 | KDM5A (0.46) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL28992207 | 0.98 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL28992339 | 0.98 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL28992327 | 0.98 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL28992184 | 0.95 | KDM5A (0.41) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL16116680 | 0.89 | KDM5A (0.45) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL27033108 | 0.89 | KDM5A (0.45) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL18027848 | 0.87 | LMNA (0.38) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL8642164 | 0.87 | LMNA (0.38) | KDM5APHF8KDM2AKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230477-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230477-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | CPT1A, LIPC, PC | KDM5A 3289/4885PHF8 3395/4885KDM2A 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.