SCHEMBL24005391

SCHEMBL24005391

NCC1CCC(N=S2(=O)CCNCC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
LMNA P02545 1/20 0.32
NCF1 P14598 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24005580 0.84 PLG (0.35) PLGPLATLMNANCF1
SCHEMBL25468658 0.84 PLG (0.35) PLGPLATLMNANCF1
SCHEMBL24005871 0.83
SCHEMBL25623224 0.80 THRA (0.33)
SCHEMBL24006076 0.79 PLG (0.32) PLGPLATLMNANCF1
SCHEMBL25481303 0.79 ALOX15 (0.33)
SCHEMBL25468463 0.74 NCF1 (0.38) NCF1
SCHEMBL20090529 0.68
SCHEMBL24005797 0.66
SCHEMBL25468461 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078398-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON PHARMACEUTICALS, LTD. (CN) 2023-05-11 WO disclosed
WO-2021223736-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON PHARMACEUTICALS, LTD. (CN) 2021-11-11 WO disclosed