Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25480486 | 0.90 | CA12 (0.34) | ALDH1A1TSHRNPSR1POLBL3MBTL1 | |
| SCHEMBL25478795 | 0.86 | NPSR1 (0.34) | ALDH1A1NPSR1POLBL3MBTL1KMT2A | |
| SCHEMBL25480485 | 0.85 | L3MBTL1 (0.38) | ALDH1A1SMN1; SMN2TSHRNPSR1POLB | |
| SCHEMBL25480489 | 0.83 | LPAR1 (0.34) | ALDH1A1TSHRNPSR1POLBHSD17B10 | |
| SCHEMBL25478792 | 0.82 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TSHRNPSR1POLB | |
| SCHEMBL25478605 | 0.79 | HTR2A (0.40) | ALDH1A1SMN1; SMN2TSHRHTTKMT2A | |
| SCHEMBL25478774 | 0.78 | HRH3 (0.33) | — | |
| SCHEMBL25478787 | 0.76 | KMT2A (0.38) | ALDH1A1POLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL24005863 | 0.76 | KMT2A (0.35) | ALDH1A1TSHRKMT2ACYP1A2CYP3A4 | |
| SCHEMBL24005491 | 0.75 | POLB (0.35) | NPSR1POLBL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |