Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25480485 | 0.89 | L3MBTL1 (0.38) | POLBL3MBTL1CA1CA2CA9 | |
| SCHEMBL25478800 | 0.87 | USP1 (0.35) | POLBL3MBTL1HTR7TMEM97NPSR1 | |
| SCHEMBL25480486 | 0.85 | CA12 (0.34) | POLBL3MBTL1CA12CA1CA2 | |
| SCHEMBL25613559 | 0.83 | CA12 (0.33) | POLBL3MBTL1CA12CA1CA2 | |
| SCHEMBL25478797 | 0.83 | HTR7 (0.35) | POLBL3MBTL1HTR7TMEM97NPSR1 | |
| SCHEMBL24005860 | 0.80 | HTR2A (0.42) | HTR7HSP90AA1LMNAHTR1A | |
| SCHEMBL25480477 | 0.77 | HRH3 (0.33) | — | |
| SCHEMBL24005504 | 0.76 | P2RX7 (0.41) | POLBALOX15HSP90AA1LMNA | |
| SCHEMBL25480336 | 0.76 | SIGMAR1 (0.36) | HTR7ALOX15 | |
| SCHEMBL24005472 | 0.75 | HTR7 (0.36) | HTR7TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |