Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 4/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005740 | 0.87 | JAK3 (0.41) | TTKJAK3MAPK1MEN1POLB | |
| SCHEMBL24005903 | 0.84 | ROCK1 (0.38) | JAK3 | |
| SCHEMBL25613060 | 0.82 | TTK (0.38) | TTKJAK3LRRK2MAPK1 | |
| SCHEMBL24005753 | 0.82 | PIK3CD (0.36) | JAK3MAPK1MEN1POLBKMT2A | |
| SCHEMBL24005911 | 0.80 | ROCK1 (0.46) | — | |
| SCHEMBL24005535 | 0.75 | BRD4 (0.43) | MAPK1MEN1POLBKMT2APIK3CD | |
| SCHEMBL25613081 | 0.73 | LRRK2 (0.41) | TTKLRRK2MAPK1BRD4GRM4 | |
| SCHEMBL24005769 | 0.71 | PIK3CA (0.36) | PIK3CDBRD4 | |
| SCHEMBL24005759 | 0.71 | FGFR1 (0.39) | GRM5LRRK2PIK3CDBRD4 | |
| SCHEMBL30428798 | 0.70 | TTK (0.38) | TTKMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |