Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25613150 | 0.82 | ULK1 (0.31) | PIK3CAPIK3CDMTOR | |
| SCHEMBL25613142 | 0.73 | PIK3CA (0.38) | PIK3CAPIK3CDMTORJAK2JAK1 | |
| SCHEMBL24005771 | 0.73 | PIK3CA (0.38) | PIK3CAPIK3CDMTORJAK2JAK1 | |
| SCHEMBL24005751 | 0.71 | TTK (0.40) | PIK3CDBRD4 | |
| SCHEMBL9887640 | 0.68 | AXL (0.42) | PIK3CAPIK3CDBRD4RIPK1FGFR1 | |
| SCHEMBL11286572 | 0.67 | AXL (0.39) | PIK3CAPIK3CDBRD4RIPK1FGFR1 | |
| SCHEMBL25613146 | 0.67 | CACNA1G (0.34) | — | |
| SCHEMBL24005741 | 0.64 | RIPK1 (0.42) | PIK3CAPIK3CDBRD4RIPK1FGFR1 | |
| SCHEMBL24005643 | 0.64 | AXL (0.37) | PIK3CAPIK3CDBRD4RIPK1JAK2 | |
| SCHEMBL25626100 | 0.64 | PIK3CA (0.52) | PIK3CAPIK3CDMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |