Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005911 | 0.89 | ROCK1 (0.46) | ROCK1PRKCZCHRM1SLC6A2 | |
| SCHEMBL24005740 | 0.88 | JAK3 (0.41) | ROCK1PRKCZJAK3 | |
| SCHEMBL24005751 | 0.84 | TTK (0.40) | JAK3 | |
| SCHEMBL24005753 | 0.83 | PIK3CD (0.36) | JAK3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25613079 | 0.82 | FEN1 (0.34) | ROCK1PRKCZJAK3CHRM1SLC6A2 | |
| SCHEMBL24005535 | 0.76 | BRD4 (0.43) | — | |
| SCHEMBL25613074 | 0.72 | PRKCZ (0.44) | ROCK1PRKCZCHRM1 | |
| SCHEMBL24005759 | 0.72 | FGFR1 (0.39) | — | |
| SCHEMBL25613062 | 0.70 | JAK3 (0.39) | ROCK1PRKCZJAK3 | |
| SCHEMBL24005743 | 0.69 | CDK8 (0.40) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |