Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25628790 | 0.85 | KCNA5 (0.31) | KCNA5KCNH2PIK3C3NUDT1 | |
| SCHEMBL25613583 | 0.83 | KCNA5 (0.32) | KCNA5KCNH2 | |
| SCHEMBL24005468 | 0.80 | ACHE (0.38) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL24005540 | 0.80 | CHRNB4 (0.38) | ATRCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL4293001 | 0.71 | CHRNB2 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL20314858 | 0.68 | IDO1 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL15990663 | 0.67 | ATR (0.53) | ATRCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL15786730 | 0.67 | ATR (0.53) | ATRCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL25478279 | 0.66 | ADRB2 (0.36) | MAPTCYP2A13KCNA5PIK3C3 | |
| SCHEMBL15999386 | 0.65 | MAPT (0.44) | MAPTKCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |