SCHEMBL240079

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL241510	0.91	MAPT (0.47)	MAPK1ALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL237497	0.89	MAPT (0.49)	MAPK1ALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL239315	0.88	HPGD (0.48)	MAPK1ALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL238260	0.88	NPBWR1 (0.43)	MAPK1ALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL239493	0.88	L3MBTL1 (0.40)	MAPK1ALDH1A1MAPTL3MBTL1LMNA
	SCHEMBL242322	0.86	KAT2B (0.40)	MAPK1ALDH1A1MAPTL3MBTL1POLB
	SCHEMBL240276	0.85	CNR1 (0.39)	MAPK1ALDH1A1MAPTL3MBTL1POLB
	SCHEMBL241278	0.82	KMT2A (0.38)	MAPK1ALDH1A1MAPTL3MBTL1POLB
	SCHEMBL237400	0.82	NPBWR1 (0.45)	MAPK1ALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL20694987	0.82	HPGD (0.36)	MAPK1ALDH1A1MAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.