Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691344 | 0.93 | GABRA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL454639 | 0.80 | NR3C1 (0.35) | GABRA1GABRB2 | |
| SCHEMBL16950506 | 0.77 | HTR2A (0.31) | — | |
| SCHEMBL17046394 | 0.77 | APOBEC3G (0.32) | — | |
| SCHEMBL16960717 | 0.73 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL7429724 | 0.72 | PRCP (0.31) | — | |
| SCHEMBL310156 | 0.72 | GABRA1 (0.47) | GABRA1GABRB2 | |
| SCHEMBL919938 | 0.71 | GABRA1 (0.45) | GABRA1GABRB2 | |
| SCHEMBL24554 | 0.71 | GABRA1 (0.45) | GABRA1GABRB2 | |
| SCHEMBL4563689 | 0.71 | GABRA1 (0.55) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588480-A2 | 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF& xA; | SANOFI (FR) | 2013-05-08 | — | — | EP | disclosed |
| WO-2011161537-A2 | 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-29 | — | — | WO | disclosed |