Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.64 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457940 | 0.81 | SIGMAR1 (0.62) | SIGMAR1HTR1AOPRL1OPRM1DRD2 | |
| SCHEMBL18402140 | 0.79 | SIGMAR1 (0.60) | SIGMAR1HTR1AOPRL1OPRM1DRD2 | |
| SCHEMBL6502218 | 0.79 | SIGMAR1 (0.65) | SIGMAR1HTR1AOPRL1DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL6489394 | 0.78 | SIGMAR1 (0.63) | SIGMAR1HTR1AOPRL1DRD2HTR2A | |
| SCHEMBL15675887 | 0.78 | OPRM1 (0.57) | SIGMAR1OPRL1OPRM1 | |
| SCHEMBL14149620 | 0.78 | OPRM1 (0.57) | SIGMAR1OPRL1OPRM1 | |
| SCHEMBL14149847 | 0.77 | OPRM1 (0.58) | SIGMAR1HTR1AOPRL1OPRM1KCNA3 | |
| SCHEMBL15704267 | 0.77 | OPRM1 (0.58) | SIGMAR1HTR1AOPRL1OPRM1KCNA3 | |
| SCHEMBL24008622 | 0.76 | HTR2C (0.39) | SIGMAR1KCNA3DRD2HTR2AHTR2C | |
| SCHEMBL24008498 | 0.75 | SIGMAR1 (0.47) | SIGMAR1HTR1AOPRL1OPRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021224864-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2021-11-11 | — | — | WO | disclosed |