Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | FHIT | P49789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400973 | 1.00 | EP300 (0.47) | EP300KAT8TRIM24TRIM33ALDH1A1 | |
| SCHEMBL2399255 | 0.98 | EP300 (0.48) | EP300KAT8TRIM24TRIM33ALDH1A1 | |
| SCHEMBL2399252 | 0.98 | EP300 (0.48) | EP300KAT8TRIM24TRIM33ALDH1A1 | |
| Lithium Ion SCHEMBL2400971 | 0.83 | TRIM24 (0.43) | EP300KAT8TRIM24TRIM33ALDH1A1 | |
| SCHEMBL2399812 | 0.82 | PTPN1 (0.52) | TRIM24TRIM33ALDH1A1FBP1KMT2A | |
| SCHEMBL2399810 | 0.82 | PTPN1 (0.52) | TRIM24TRIM33ALDH1A1FBP1KMT2A | |
| SCHEMBL12086582 | 0.79 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1KMT2ATDP1 | |
| SCHEMBL2787808 | 0.79 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1KMT2ATDP1 | |
| SCHEMBL2787807 | 0.79 | TRIM24 (0.52) | TRIM24TRIM33ALDH1A1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL994965 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TBXAS1FBP1RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012967-B2 | Minor groove binders | UNIVERSITY OF STRATHCLYDE (GB) | 2011-09-06 | — | — | US | disclosed |
| US-20100016311-A1 | NOVEL MINOR GROOVE BINDERS | UNIVERSITY OF STRATHCLYDE (GB) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016311-A1 | NOVEL MINOR GROOVE BINDERS | TOP2B, DNA2, CTCF | EP300 148/4885KAT8 1854/4885TRIM24 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.