Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010077 | 0.88 | KCNH2 (0.35) | KCNH2ALDH1A1MAPTHTT | |
| SCHEMBL12471392 | 0.82 | ALDH1A1 (0.41) | KCNH2ALDH1A1MAPTHTT | |
| SCHEMBL21870609 | 0.79 | SMYD3 (0.33) | HTT | |
| SCHEMBL18844874 | 0.75 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL469045 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTHTT | |
| SCHEMBL12409575 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTHTT | |
| SCHEMBL25042763 | 0.72 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL1142602 | 0.72 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL549384 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL21879630 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021225969-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |