SCHEMBL24010953

SCHEMBL24010953

CCSc1cc(CC)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.57
POLB P06746 1/20 0.41
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
ALOX15 P16050 3/20 0.38
HSD17B10 Q99714 3/20 0.38
DAO P14920 2/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
ALOX12 P18054 2/20 0.38
HTT P42858 2/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
BACE1 P56817 1/20 0.38
MEN1 O00255 2/20 0.36
HPGD P15428 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11092961 0.84 TRPA1 (0.57) TRPA1POLBALOX15HSD17B10DAO
SCHEMBL7565930 0.83 TRPA1 (0.61) TRPA1POLBCNR1CNR2ALOX15
SCHEMBL10888353 0.78 MEN1 (0.38) TRPA1ALOX15HSD17B10ALDH1A1GAA
SCHEMBL10470094 0.76 ALOX15 (0.45) POLBALOX15HSD17B10ALDH1A1GAA
SCHEMBL5988981 0.74 TRPA1 (0.50) TRPA1POLBALOX15HSD17B10ALDH1A1
SCHEMBL27353332 0.73 TRPA1 (0.39) TRPA1ALDH1A1GAAMAPTKDM4E
SCHEMBL56556 0.73 TRPA1 (1.00) TRPA1POLBCNR1ALOX15HSD17B10
SCHEMBL30290839 0.73 TRPA1 (1.00) TRPA1POLBCNR1ALOX15HSD17B10
SCHEMBL10503140 0.73 ALDH1A1 (0.53) ALOX15HSD17B10ALDH1A1GAAMAPT
SCHEMBL11659597 0.73 MAPT (0.52) TRPA1POLBALOX15HSD17B10DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728532-B1 ODOROUS ACETALS OF ETHYL VANILLIN AND ETHYL VANILLIN DERIVATIVES S H KELKAR AND COMPANY LTD (IN) 2021-11-10 EP disclosed