Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011331 | 1.00 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL24011484 | 1.00 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL24011432 | 0.94 | MAPT (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL26633720 | 0.89 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL26764371 | 0.89 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL30288091 | 0.89 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL24011392 | 0.89 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL24011658 | 0.89 | NPC1 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB | |
| SCHEMBL24011040 | 0.89 | LMNA (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1POLB | |
| SCHEMBL24011501 | 0.88 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | RAB9A 814/4885SMN1; SMN2 610/4885NPC1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.