SCHEMBL24017155

SCHEMBL24017155

CNC(c1cccc2ccccc12)C(N)c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SLC6A4 P31645 2/20 0.44
AOC3 Q16853 1/20 0.43
CASR P41180 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
KRAS P01116 1/20 0.37
SOS1 Q07889 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24016992 0.87 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL24017144 0.80 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL9906119 0.80 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL2067587 0.80 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL29887508 0.80 ALDH1A1 (0.60) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
Hydrochloric Acid SCHEMBL14119362 0.78 ALDH1A1 (0.58) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
Hydrochloric Acid SCHEMBL30098262 0.78 ALDH1A1 (0.58) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
Hydrochloric Acid SCHEMBL19951713 0.78 ALDH1A1 (0.58) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL11817158 0.77 ALDH1A1 (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL12601482 0.74 GABRA1 (0.47) ALDH1A1CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021223156-A1 DIBORON GLYCOL ESTER, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2021-11-11 WO disclosed