Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403512 | 0.98 | ALDH1A1 (0.61) | ALDH1A1POLBCHRM1CNR1HRH3 | |
| SCHEMBL2401347 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CHRM1CNR1HRH3MEN1 | |
| SCHEMBL2405450 | 0.83 | DRD2 (0.55) | ALDH1A1POLBCNR1MEN1KMT2A | |
| SCHEMBL2401119 | 0.83 | ALDH1A1 (0.50) | ALDH1A1POLBHRH3MEN1KMT2A | |
| SCHEMBL2401122 | 0.83 | ALDH1A1 (0.50) | ALDH1A1POLBHRH3MEN1KMT2A | |
| SCHEMBL2404100 | 0.82 | CNR1 (0.47) | ALDH1A1POLBCNR1MEN1KMT2A | |
| SCHEMBL2404102 | 0.82 | CNR1 (0.47) | ALDH1A1POLBCNR1MEN1KMT2A | |
| SCHEMBL2405877 | 0.81 | KMT2A (0.58) | ALDH1A1POLBCHRM1HRH3MEN1 | |
| SCHEMBL2405879 | 0.81 | KMT2A (0.58) | ALDH1A1POLBCHRM1HRH3MEN1 | |
| SCHEMBL2402205 | 0.81 | ALDH1A1 (0.50) | ALDH1A1POLBCHRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017773-B2 | Cyclohexyl sulfonamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20070173511-A1 | Cyclohexyl sulfonamide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173511-A1 | Cyclohexyl sulfonamide derivatives | HRH3, HRH4, HRH1 | ALDH1A1 430/4885POLB 4404/4885CHRM1 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.