Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19538744 | 0.86 | LMNA (0.67) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19520585 | 0.85 | ALDH1A1 (0.68) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19538809 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL19520353 | 0.82 | ALDH1A1 (0.59) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19520349 | 0.82 | LMNA (0.53) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19520405 | 0.81 | ALDH1A1 (0.56) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19520375 | 0.81 | ALDH1A1 (0.55) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19520410 | 0.79 | TSHR (0.64) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19520586 | 0.79 | TSHR (0.52) | LMNAALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL19549073 | 0.79 | MAPT (0.71) | LMNAALDH1A1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448853-B1 | COMPOUNDS FOR MODULATING AQUAPORINS | APOGLYX AB (SE) | 2021-11-17 | — | — | EP | disclosed |